Blueberries are recognized for their wholesome antioxidants, nutritional value and dietary fiber. But little is known about the benefits of pterostilbene, a chemical found in those delicious berries as well as in grapes. Pterostilbene chemically referred to as 3, 5-dimethoxy-4-hydroxystilbene is a derivative of resveratrol, and scientific studies performed on animals subjects as well as in vitro have displayed positive outcomes for the prevention of certain types of cancer, Alzheimer’s, and cardiovascular diseases.
Cancer in Breast and Pancreas
Pterostilbene suppresses the development of your breast cancer tumors and also stimulates their death, based on an in vitro review that was released in April 2012 edition of “The Journal of Clinical Research.”
A further research review, highlighted in the May 2012 publication of the same journal assessed the benefits of pterostilbene along with epigallocatechin-3-gallate (EGCG), the important substance found in green tea. The experts determined that both of these chemicals come with an compounding effect in eliminating the development of malignant pancreatic cancer cell tissues, along with promoting the cancerous cells’ death in vitro. Even more research is essential to assess the feasible utilization of EGCG and pterostilbene to enhance conventional treatments for pancreatic cancer malignancy.
In the University of Medical Science, Poznañ, Poland, researchers revealed that pterostilbene’s cancer-inhibiting substance could be associated with its capability to inhibit a enzyme known as “cytochrome P450.” This enzymes has a key function in the initiation a number of substances generally known as “Procarcinogens,” which turn chemical substances such as those found in cigarettes and pesticide sprays, for example, into carcinogens.
Being that resveratrol has shown positive results on battling Alzheimer’s disease and has many commonalities with pterostilbene; experts in the Department of Neuroscience in Cleveland, Ohio evaluated the results of those two substances for Alzheimer’s disease. The study discovered that pterostilbene can be a stiffer modulator of cognition along with cellular stress as compared to resveratrol. This research was performed on animal subjects, and was released in the October 2011 edition with “Neurobiology of Aging.”
Effective for Cardiovascular Diseases
Chemist Agnes Rimando of ARS Natural Products Utilization Research Laboratory in Oxford Mississippi says, “The better we study the benefits of pterostilbene, the greater we understand its enormous potential within the human health area,” As well as its anti-cancer characteristics, Rimaldo mentioned that pterostilbene could help reduce levels of cholesterol which will help prevent heart diseases. This particular conclusion had been based on research done on animal subjects and studied how pterostilbene exhibited similar outcomes to ciprofibrate, a medication employed for the treatments for tryglycerides and high LD cholestrerol levels. Rimaldo research also suggests that pterostilbene could have fewer side effects in comparison with traditional drugs. Considering that higher triglycerides levels are associated with cardio-vascular events, pterostilbene may possibly prevent coronary heart diseases as well.
Though this research carried out animal subjects and in tubes is demonstrating motivating results, research in humans is necessary to fully validate these health advantages of pterostilbene. Moreover, pterostilbene seems to be even more healthy then resveratrol. Remember that blueberries may also be packed with phytonutrients, nutritional vitamins like riboflavin and niacin, minerals including iron, calcium, potassium, magnesium, phosphorus, magnesium as well as significant amounts of fibers. Enjoy a cup of fresh organic blueberries each day for the best benefits.
Pterostilbene is available at my online store, by clicking here.
- “The Journal of Clinical Research.” ; Inhibitory effects of (-)-epigallocatechin-3-gallate and pterostilbene on pancreatic cancer growth in vitro; SF Kostin et al; May, 2012 http://www.ncbi.nlm.nih.gov/pubmed/22583593
- “The Journal of Clinical Research”; Pterostilbene induces mitochondrially derived apoptosis in breast cancer cells in vitro; D Moon et al; April, 2012 http://www.ncbi.nlm.nih.gov/pubmed/22572619
- “Neurobiology of Aging.” Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer’s disease; J. Change et al; October, 2011 http://www.ncbi.nlm.nih.gov/pubmed/21982274
- USDA; Pterostilbene’s Healthy Potential; Agricultural Research Nov-Dec, 2006 http://www.ars.usda.gov/is/AR/archive/nov06/health1106.htm